Many high-throughput applications, such as sequencing and genotyping, require the input DNA concentration to be within a certain range for optimal results. Traditionally, a tedious process of quantification, calculation and concentration adjustment must be carried out to normalize the DNA samples.
The Mag-Bind® EquiPure Normalizer Kit completely eliminates the need to quantify and aliquot DNA, saving time, quantification bias and tip cost. Using our proprietary Mag-Bind® Normalizer Beads and binding buffer system, input DNA of various quantities is simply bound, washed and eluted to a final normalized product. The magnetic beads have a limited binding capacity and therefore allow a predefined amount of DNA to be captured and eluted.
The Mag-Bind® EquiPure Normalizer Kit is fully automatable on multiple liquid handling platforms including Hamilton STAR, Tecan Fluent™, Caliper Sciclone, and Beckman Coulter Biomek instruments.
The Mag-Bind® EquiPure Normalizer Kit allows the user to adjust the quantity of DNA that binds to the magnetic beads and elution volumes can be adjusted to vary DNA concentrations to users needs.
*DNA output concentrations: +/- 10%
*No quantification required
*Normalizes genomic DNA or NGS libraries
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