CaLiVax-DOTAP is a cationic lipid-based composition for liposome-mediated DNA or protein vaccines.
Cationic Liposome-DOTAP Adjuvant: average size of 100 nm.
DOTAP (N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N trimethyl-ammonium methyl-sulfate):Cholesterol (1:1 molar ratio) cationic lipid composing this genetic adjuvant allows the formation of complexes with plasmid DNA or antigen protein to form an efficient lipoplexes-based nanoparticle delivery system (LPD).
LDP are non-viral gene delivery systems, self-assembled from cationic liposomes and negatively charged immunogen that function as vaccine carrier.
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